Asian Journal of Research in Pharmaceutical Sciences

K. Girish Pai ¹, T. Vamshi Krishna ¹, Lalit Kumar ¹, M. Sreenivasa Reddy ¹, Shreya Singh ¹, V. Vibha ¹

Affiliations
1 Department of Pharmaceutics, MCOPS, Manipal University, Manipal, Karnataka-576104, IN

Abstract

The objective of the study was to assess whether few marketed brands of Salbutamol sulphate syrup IP was within the limits as specified in Indian Pharmacopoeia with respect to selected physical parameters. A study was carried out using two different brands coded as brand A and B for Salbutamol sulphate syrup IP. In this study, selected brands were well known brands and a comparative study was planned. Salbutamol is a short acting β2 adrenergic receptor agonist used commonly for the relief of bronchospasm in conditions such as asthma and Chronic Obstructive Pulmonary Disease (COPD). In the present study, three different batches each of brand A and brand B were procured randomly from the medical shop. The tests that were performed included the visual inspection or appearance of product, pH measurement, extractable volume, primary labeling quality and checking of text matter on primary label. From the study, it was found that both the brands were comparable with respect to various physical parameters; however brand B was chosen as best since the results for all three batches were consistent and uniform. Brand A was not user friendly since there was difficulty in opening cap as it is uncomfortable for a patient suffering from asthma. These types of problems sometimes receive market complaints as well.

Keywords

Salbutamol Sulphate, Copd, Extractable Volume, Text Matter.

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Lalit Kumar ¹, Deepak Prashar ¹

Affiliations
1 Department of Pharmaceutical Sciences, Vinayaka College of Pharmacy, Kullu, (H.P.), IN

Abstract

From a last decade a lot of work is going on the indanol ring. Scientists have developed large number of new compounds related to this moiety and screened them for their different pharmacological activities to get a molecule which have good pharmacological activity and lesser side effects. This review article reflects various pharmacological activities of indanol derivatives. This indanol has shown its importance as antimicrobial, anti-fungal, antiviral, antitubercular, anti-inflammatory, anti-HIV, CNS depressant, Analgesic, Hypnotics and Antipsychotic activities.

Keywords

Indanol, Antimicrobial, Anti-Fungal, Antiviral, Antitubercular, Anti-Inflammatory, Anti-HIV, Antipsychotic, Etc.

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